NCT05257824

Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling

Optimal Duration of Dual Antiplatelet Therapy After Stent-assisted Coiling of Unruptured Intracranial Aneurysms: A Prospective Randomized Multicenter Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 528 (actual)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Comparison of duration of dual antiplatelet therapy after stent-assisted coiling of unruptured intracranial aneurysms

Detailed description

The purpose of this study is to compare the incidence of thromboembolic and hemorrhagic complications between 1 and 18 months after stent-assisted coiling according to the duration of use of dual antiplatelet agents (6 months versus 12 months) after stent-assisted coiling of unruptured intracranial aneurysms to determine the optimal duration of use of dual antiplatelet agents.

Conditions

• Aneurysm Cerebral
• Endovascular Procedures

Interventions

Type	Name	Description
DRUG	Aspirin 100mg	1. short-term dual antiplatelet: dual antiplatelet agents for 6 months 2. long-term dual antiplatelet: dual antiplatelet agents for 12 months
DRUG	Clopidogrel 75mg	1. short-term dual antiplatelet: dual antiplatelet agents for 6 months 2. long-term dual antiplatelet: dual antiplatelet agents for 12 months

Timeline

• Start date: 2022-06-23
• Primary completion: 2025-12-02
• Completion: 2025-12-02
• First posted: 2022-02-25
• Last updated: 2025-12-19

Locations

8 sites across 1 country: South Korea