NCT05257330

Evaluation of Non-Compressive Myelopathy in a Sample of Egyptian Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 2 Months – 100 Years
• Healthy volunteers: Not accepted

Summary

An observational study will be conducted in the Department of Neurology at AlAzhar University Hospitals To study the etiological factors of non-compressive myelopathy in a sample of Egyptian patients

Detailed description

Myelopathy is a collective term referring to any pathologic condition or neurologic deficit related to the spinal cord. Myelopathies are a frequent and potentially disabling neurologic emergency.(Sarbu et al., 2019). Diseases of the spinal cord often have devastating consequences and imaging studies are indispensable for their diagnosis. The diagnostic approach must be based on the clinical context, the time elapsed since the onset of symptoms and signs, and the imaging findings (Herrera et al., 2020). Myelopathies may be compressive or non-compressive, regarding to subarachnoid space obstruction (Kundu et al., 2018). Noncompressive myelopathy (NCM) is described as "spinal cord involvement without detectable clinical and radiological evidence of spinal cord compression causing neurological deficit (Thangaraj et al., 2019). There have been a few studies that have investigated Noncompressive myelopathy (NCM) in Africa as part of nontraumatic myelopathy. With very few studies focusing on NMOSD, Most of them focus on extrinsic compression and infectious diseases as important causes of myelopathy (Musubire et al., 2021) Comprehensive data on Egyptian patients with Non-compressive myelopathy (NCM) in the light of newer diagnostic criteria and serological tests are lacking. No study has been conducted to study the clinico-radiological profile of Non-compressive myelopathy (NCM) so far. In this study, we are putting an effort to convey our experience on etiological pattern of Non-compressive myelopathy (NCM) with special reference to its radiological features.

Conditions

• Myelopathy
• Non-Compressive

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	CSF Examination	Lumbar puncture for CSF Examination

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-06-30
• Completion: 2022-07-31
• First posted: 2022-02-25
• Last updated: 2022-02-25

Locations

1 site across 1 country: Egypt