NCT05257109

Water Content in E-Liquids

Water Content In E-Liquids

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

This study looks at the effect of manipulating the water concentration of certain e-liquids on sensory perception.

Detailed description

This study looks at the effect of manipulating water concentration on e-cigarettes that contain aldehyde flavor chemicals on sensory perception. Regular e-cigarette users will be asked to complete 2 lab sessions in which they will sample 4 nicotine containing e-liquids. Each e-liquid will be sampled in four water concentration manipulations. Researchers will examine influence of flavor and water concentrations on sensory experience including appeal/liking and irritation and harshness.

Conditions

• Nicotine E-Cigarette Use

Interventions

Type	Name	Description
OTHER	Water Concentration 1	E-liquid containing 36mg/ml pronated nicotine will be administered with no alteration to water concentration.
OTHER	Water Concentration 2	E-liquid containing 36mg/ml pronated nicotine will be administered with 5% total water concentration of e-liquid.
OTHER	Water Concentration 3	E-liquid containing 36mg/ml pronated nicotine will be administered with 10% total water concentration of e-liquid.
OTHER	Water Concentration 4	E-liquid containing 36mg/ml pronated nicotine will be administered with 20% total water concentration of e-liquid.

Timeline

• Start date: 2022-08-01
• Primary completion: 2023-03-10
• Completion: 2023-03-10
• First posted: 2022-02-25
• Last updated: 2024-10-22
• Results posted: 2024-10-22

Locations

1 site across 1 country: United States