NCT05256563

A Biomarker for Personalized Care in Post-Stroke Spatial Neglect

A Biomarker for Personalized Care in Post-stroke Spatial Neglect

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 45 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

More than 30,000 Veterans are hospitalized for stroke each year, and in the critical first months of recovery, at least half are disabled by abnormal 3-D spatial function (spatial neglect). Their self-care, mobility, and ability to return home are severely limited.

Detailed description

Spatial Neglect (SN)is an underdiagnosed stroke-related condition--and a specific core set of symptoms--Aiming Spatial Neglect-- may have a major adverse effect on outcome. These same symptoms may predict excellent response to spatial neglect therapy. The investigators seek to develop a biological parameter for treatment assignment. In this two-year study, the investigators will enroll 45 people with right brain stroke who are at high risk of SN. The investigators will examine clinical brain images, behavioral assessment and research brain images at baseline and recovery at 3 and 6 months after study entry.

Conditions

• Spatial Neglect
• Stroke

Timeline

• Start date: 2021-09-01
• Primary completion: 2026-07-31
• Completion: 2027-07-31
• First posted: 2022-02-25
• Last updated: 2026-02-03

Locations

1 site across 1 country: United States