NCT05252962

Investigation of the Bioavailability of Marine Based Collagen Peptides in Healthy Subjects

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Rousselot BVBA · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate the relative bioavailability of Peptan® Type I collagen peptides from different marine origin (different fish sources, production process and molecular weight) in healthy human subjects.

Detailed description

The aim of this study is to evaluate the relative bioavailability of different Peptan® Type I collagen peptides in healthy human subjects. The pharmacokinetic parameters AUC0-6h, Cmax and Tmax will be determined from the concentration-time curves of characteristic collagen markers (e.g. hydroxyproline, proline, glycine, di- and tripeptides together with further amino acids) after oral single dose administration. The following objectives will be evaluated by comparison of pharmacokinetic parameters between the products: * The impact of different production processes * The impact of size of collagen peptides * The impact of different fish sources

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Collagen Peptides	Collagen peptides will be orally administered and pharmacokinetic parameters will be assessed up to 6 hours after study product intake.

Timeline

• Start date: 2021-11-26
• Primary completion: 2022-02-17
• Completion: 2023-05-17
• First posted: 2022-02-23
• Last updated: 2024-12-17

Locations

1 site across 1 country: Germany