Trials / Terminated
TerminatedNCT05251233
Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
Evaluation of the Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 56 (actual)
- Sponsor
- Washington University School of Medicine · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to prospectively determine the effects of administering proton pump inhibitors (PPIs) following pancreaticoduodenectomy on postoperative outcomes. The findings of this study will help in avoiding the widespread use of PPIs during the immediate postoperative period following pancreatic surgery.
Conditions
- Pancreatic Cancer
- Pancreas Cancer
- Ampullary Cancer
- Pancreas Neuroendocrine Tumor
- Pancreatitis
- Distal Extrahepatic Cholangiocarcinoma
- Duodenal Cancer
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Placebo | Placebo capsules contain pharmaceutical-grade lactose monohydrate NF, a naturally occurring disaccharide of galactose bound to glucose. |
| DRUG | Pantoprazole | The study will use commercial supply. |
Timeline
- Start date
- 2022-04-21
- Primary completion
- 2024-06-29
- Completion
- 2024-06-29
- First posted
- 2022-02-22
- Last updated
- 2025-05-06
- Results posted
- 2025-05-06
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT05251233. Inclusion in this directory is not an endorsement.