NCT05247775

Urethral Functional Profile Length Before Radical Prostatectomy as an Early Postoperative Continence Predictor

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Clinical Hospital Centre Zagreb · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Urinary incontinence (UI) is one of the most common complications of radical prostatectomy (RP). Impaired urethral sphincter function is generally considered to be the most important contributing factor of UI however, the mechanism of onset and recovery of urinary continence has not been fully elucidated. In this research, the urodynamic method of Urethral Pressure Profile (UPP) was used to evaluate Functional Urethral Length (FUL) and Maximal Urethral Closure Pressure (MUCP) and correlate with the postprostatectomy continence recovery. Objective of this research is to evaluate preoperative FUL and MUCP as an early continence recovery predictors after open retropubic RP (ORRP). The research was conducted at the Department of Urology of the University Hospital Centre Zagreb on a group of 43 patients in the period from July 15th , 2019 to May 07th , 2021.The severity of UI and bothersome were assessed using fully validated International Consultation on Incontinence Questionnaire - Urinary Incontinence Short Form (ICIQ-UI SF) and number of pads used in 24h. Patients were interviewed about the use of urinary pads and asked to fill out the ICIQ-UI SF before and 2, 8, 16 and 24 weeks after RP.

Conditions

• Urinary Incontinence

Interventions

Type	Name	Description
PROCEDURE	Profilometry	Profilometry was performed in 43 patients before open retropubic radical prostatectomy.

Timeline

• Start date: 2019-07-15
• Primary completion: 2020-11-01
• Completion: 2021-05-07
• First posted: 2022-02-21
• Last updated: 2022-02-21

Locations

1 site across 1 country: Croatia