NCT05243238

Hesperidin and Diosmin Effect on Metabolic Syndrome

Hesperidin-Diosmin Effect on Metabolic Syndrome and Diabetic Neuropathy Among Patients With Type 2 Diabetes Mellitus

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 129 (actual)
• Sponsor: Beni-Suef University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The components of metabolic syndrome (MetS), particularly obesity and dyslipidemia, are linked to peripheral neuropathy (PN) among patients with diabetes or even without diabetes. Several studies revealed that complementary and herbal medicine could provide a potential for PN management and MetS components. Thus, designing clinical trials with interventions combinations to achieve a considerable improvement is highly recommended. Hesperidin and diosmin, citrus-derived flavonoids, have been reported to possess anti-hyperlipidemic, anti-inflammatory, analgesic, antioxidant, antidiabetic, and anti-hypertensive effect with high tolerability and safety profile

Conditions

• Metabolic Syndrome and Diabetic Neuropathy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	dietary supplement flavonoids	patients were allocated to receive either hesperidin, diosmin, or combination of both and the fourth group was assigned as a control group without intervention

Timeline

• Start date: 2020-03-01
• Primary completion: 2020-11-30
• Completion: 2021-11-12
• First posted: 2022-02-17
• Last updated: 2022-02-17

Locations

1 site across 1 country: Egypt