NCT05242510

Evaluation of Exotropia After Patching the Eye or After Prism Adaptation

Divergence Excess/Simulated Divergence Excess Exotropia (DESDEE)

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 1 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 17 Years
• Healthy volunteers: Not accepted

Summary

This study intends to determine the number and percent of subjects initially diagnosed with divergence excess exotropia which would be reclassified as simulated divergence excess exotropia if tested after 24 hours of monocular occlusion (patching) or after prism adaptation for the distance angle.

Conditions

• Exotropia

Interventions

Type	Name	Description
PROCEDURE	Patching	The subject will occlude the non-dominant eye for 24 hours.
PROCEDURE	Prism Adaptation	The subject will undergo prism adaptation targeting the pre-occlusion distance angle for 1-2 weeks. • Fresnel prism(s) will be applied to the patient's spectacles equaling the distance angle between the two eyes. At the examiner's discretion depending on the size of the deviation, the prism(s) can be placed solely over the non-dominant eye, or split between the 2 eyes in some combination which results in equalization of the distance exotropia. If the distance angle calls for an amount of prism that cannot be exactly replicated with Fresnel prisms (e.g., 32 PD), the amount of prism used will be determined by rounding down to the nearest practical amount at examiner discretion.

Timeline

• Start date: 2024-08-27
• Primary completion: 2024-09-18
• Completion: 2024-09-18
• First posted: 2022-02-16
• Last updated: 2025-04-04

Locations

9 sites across 5 countries: United States, Canada, India, Israel, Italy