NCT05241626

AS-OCT of the Cornea in Thyroid Diseases

Anterior Segment Optical Coherence Tomography Study of the Tear Film and Cornea in Thyroid Eye Diseases.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 70 (estimated)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

use the anterior segment optical coherence tomography (AS-OCT) to evaluate the tear meniscus parameters, total corneal thickness (CT), and epithelial thickness in active and inactive thyroid eye diseases (TED) patients and compare them with age-matched controls.

Detailed description

A prospective case-control clinical study. The study subjects were divided into 3 groups, group 1 of inactive thyroid patients, group 2 of active thyroid patients, and group 3 of healthy controls. The AS-OCT was used to measure lower tear meniscus parameters (tear meniscus height (TMH), tear meniscus depth (TMD), and tear meniscus area (TMA)), total CT and epithelial thickness

Conditions

• Thyroid Eye Disease

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	AS-OCT	Optical Coherence Tomography (OCT) creates detailed cross-sectional images of the anterior and posterior segments using low coherence interferometry. OCT is a noninvasive, real-time method for evaluating the tear meniscus, total corneal thickness (CT), and corneal epithelial thickness

Timeline

• Start date: 2021-05-11
• Primary completion: 2022-10-29
• Completion: 2022-10-29
• First posted: 2022-02-16
• Last updated: 2022-02-16

Locations

2 sites across 1 country: Egypt