Clinical Trials Directory

Trials / Terminated

TerminatedNCT05238025

MVA-BN-RSV Vaccine Trial

A Randomized, Double-blind, Phase 3 Trial to Assess Clinical Efficacy, Safety and Reactogenicity of the Recombinant MVA-BN® -RSV Vaccine in Adults ≥60 Years of Age

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
20,419 (actual)
Sponsor
Bavarian Nordic · Industry
Sex
All
Age
60 Years
Healthy volunteers
Accepted

Summary

Phase 3 randomized, double blind study comparing recombinant MVA-BN-RSV vaccine vs placebo for efficacy and safety in adults \>=60 years of age

Conditions

Interventions

TypeNameDescription
BIOLOGICALMVA-BN-RSV vaccineOne injection, suspension for injection, intramuscular use, 0.5mL MVA-BN-RSV virus with a titer of at least 3 x 10E8 infectious units (Inf.U)/0.5mL in a Tris buffer at pH 7.7.
BIOLOGICALTris Buffered Saline (TBS)One injection, solution for injection, intramuscular use, 0.5mL TBS, pH 7.7.

Timeline

Start date
2022-04-19
Primary completion
2023-06-29
Completion
2023-09-01
First posted
2022-02-14
Last updated
2024-10-31
Results posted
2024-10-31

Locations

120 sites across 2 countries: United States, Germany

Regulatory

Source: ClinicalTrials.gov record NCT05238025. Inclusion in this directory is not an endorsement.