Trials / Unknown
UnknownNCT05237791
Effect of Magnesium on Remifentanil Induced Cough
Effect of Magnesium Sulfate on Remifentanil Induced Cough and Chest Wall Rigidity
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 78 (estimated)
- Sponsor
- Seoul National University Bundang Hospital · Academic / Other
- Sex
- All
- Age
- 20 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The hypothesis of this study is that Magnesium sulfate pretreatment (50mg/kg) will reduce the incidence of cough and chest wall rigidity caused by remifentanil administration. The purpose of this study was to investigate the effect of magnesium sulfate administered before induction of anesthesia on thoracic stiffness and cough response caused by opioid analgesics administered for general anesthesia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Magnesium sulfate | magnesium sulphate 50mg/kg (loading dose for 10 minutes), 15mg/kg/hr (continuous infusion) |
| DRUG | Placebo | normal saline 100ml (loading dose for 10 minutes), 15mg/kg/hr (continuous infusion) |
Timeline
- Start date
- 2022-02-03
- Primary completion
- 2022-06-30
- Completion
- 2022-12-30
- First posted
- 2022-02-14
- Last updated
- 2022-02-14
Source: ClinicalTrials.gov record NCT05237791. Inclusion in this directory is not an endorsement.