NCT05234515

Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure

Prospective Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 21 (actual)
• Sponsor: London North West Healthcare NHS Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective observational study of patients undergoing planned surgery for intestinal failure. The aims of the study are: * To prospectively characterise preoperative bacterial populations amongst patients undergoing surgery for intestinal failure * To examine the relationship between preoperative bacteriology and surgical site infection (SSI) in this patient group * To investigate the effect of surgery and surgical site infection on generic and wound specific quality of life measures

Conditions

• Surgical Wound Infection
• Surgical Site Infection
• Bacteria Infection Mechanism
• Intestinal Disease
• Intestinal Fistula

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Microbiology swab	Patients will have swabs taken from the nose, mouth, umbilical skin, groin skin, fistula(e), stoma(s) and vascular access device prior to surgery. Patients will be followed for 90 days postoperatively for surgical site infection (SSI) as defined by the centre for disease control (CDC) criteria 2021. Patients who develop an SSI will have both preoperative and postoperative samples sent for genome sequencing.
OTHER	Questionnaire	Patients will complete baseline preoperative questionnaires which will be repeated at 30 days and 90 days. These will evaluate generic and wound specific quality of life as well as decision conflict/decision regret.

Timeline

• Start date: 2022-01-14
• Primary completion: 2022-10-30
• Completion: 2023-02-20
• First posted: 2022-02-10
• Last updated: 2023-04-18

Locations

1 site across 1 country: United Kingdom