NCT05230095

Social Cognition Dysfunctions in Parkinson's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 24 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Parkinson's disease (PD) is usually responsible of cognitive and behavioral non-motor signs with a major impact on the quality of life. Social cognition is a complex system relying on emotion recognition (neurons mirror system (NMS)), the theory of mind (with its two parts: emotional and cognitive), but also on the social and cultural environment and the personal history. The first step in this model is represented by the NMS, which seems to be altered in PD patients for both positive and negative emotions as shown in our preliminary study. The investigator purpose is to investigate the role of the treatment (levodopa and deep brain stimulation) on the functioning of the NMS

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
BEHAVIORAL	social cognition tests	The evaluation of social cognition will be carried out using questionnaires and a point lights computer test. During the computer test, participants have to watch several short sequences of interactions between two silhouettes and give an interpretation of the scene. Patients will be evaluated twice: one time before the surgery and a second time 1 year after surgery. Healthy volunteers will be evaluated only one time.
BEHAVIORAL	Quality of life self-questionnaire	Quality of life will be assessed using a self-administered questionnaire in the patients group only.

Timeline

• Start date: 2022-04-11
• Primary completion: 2024-01-23
• Completion: 2024-01-23
• First posted: 2022-02-08
• Last updated: 2024-02-07

Locations

1 site across 1 country: France