NCT05229744

Prevalence of Endolymphatic Hydrops With a Hitory of Congenital Cytomegalovirus Infection

Prevalence of Endolymphatic Hydrops in Patients With a History of Congenital Cytomegalovirus Infection With Symptomatic Cochleo-vestibular Involvement

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 18 (actual)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 6 Months
• Healthy volunteers: Not accepted

Summary

The management of patients with a history of congenital CMV infection (whether symptomatic or asymptomatic at birth) is modeled on their usual management.

Detailed description

The management of patients with a history of congenital CMV infection (whether symptomatic or asymptomatic at birth) is modeled on their usual management. Patients benefit as part of the care: * A clinical cochleo-vestibular examination * Functional otoneurological explorations: audiogram, caloric tests, vHIT, otolithic evoked potentials * From an uninjected brain MRI Participation in this research entails the addition of an MRI sequence and an injection of contrast product (Gadovist®): \- 3D FLAIR MRI sequence dedicated to the exploration of the inner ear, lasting 6min30s, performed 4 hours after the initial injection of contrast product.

Conditions

• Endolymphatic Hydrops

Interventions

Type	Name	Description
DEVICE	sequence MRI 3D FLAIR	Participation in this research entails the addition of an MRI sequence and an injection of contrast product (Gadovist®): \- 3D FLAIR MRI sequence dedicated to the exploration of the inner ear, lasting 6min30s, performed 4 hours after the initial injection of contrast product

Timeline

• Start date: 2022-12-15
• Primary completion: 2025-04-22
• Completion: 2025-04-22
• First posted: 2022-02-08
• Last updated: 2026-01-06

Locations

2 sites across 1 country: France