NCT05226520

Psychophysiological Effects of Probiotic Supplementation

Effect of 6-week Probiotic Supplementation on Stress-related Parameters in Healthy Adults With Different Levels of Stress

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 49 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 25 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This is a pilot exploratory study to investigate the effects of a probiotic Bifidobacterium longum NCC3001 intake on physiological and psychophysiological parameters related to stress in healthy individuals with mild to moderate stress level.

Detailed description

The purpose of the study is to explore the effects of a probiotic Bifidobacterium longum NCC3001 intake on physiological and psychophysiological parameters related to stress in healthy individuals with mild to moderate stress level. The objectives is three: * Measure the effects of a 6-week supplementation with NCC3001 on psychological and physiological parameters in response to an acute experimental stress; * Measure the effects of a 6-week supplementation with NCC3001 on chronic stress level, gastro-intestinal symptoms and sleep quality; * Explore changes in the profiles of biological parameters associated with ingestion of NCC3001; including changes in hormones, neurotransmitters, circulating immune and microbiome-derived molecules and changes in the microbiome itself

Conditions

• Mild to Moderate Levels of Stress

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Experimental probiotic product	Probiotic supplementation
OTHER	Placebo comparator	Placebo

Timeline

• Start date: 2020-12-16
• Primary completion: 2021-12-22
• Completion: 2022-05-31
• First posted: 2022-02-07
• Last updated: 2022-07-15

Locations

1 site across 1 country: Switzerland