NCT05224583

Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant

Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant Recipients: A Retrospective Single-Center Review

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Methodist Health System · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: —

Summary

The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%.

Detailed description

The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%. Immunosuppression reduction is the management cornerstone for BKV and has been shown to be effective at clearing the virus while maintaining graft function in both kidney alone and simultaneous kidney-pancreas transplant recipients. However, there is a lack of published data on the prevalence and outcomes in simultaneous liver-kidney (SLK) transplant recipients.

Conditions

• Polyomavirus Infections
• BK Viremia
• Liver Transplant Infection
• Kidney Transplant Infection

Interventions

Type	Name	Description
PROCEDURE	Simultaneous Liver-Kidney Transplant	Simultaneous Liver-Kidney Transplant

Timeline

• Start date: 2021-11-17
• Primary completion: 2027-11-17
• Completion: 2028-11-17
• First posted: 2022-02-04
• Last updated: 2026-03-20

Locations

1 site across 1 country: United States