NCT05223907

Safety and Efficacy of Maintenance of Etomidate in General Anesthesia

Safety and Efficacy of Maintenance of Etomidate Combined With Sevoflurane in General Anesthesia: a Multi-center Randomized Controlled Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,080 (actual)
• Sponsor: Henan Provincial People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study was designed to use etomidate combined with sevoflurane intravenously to maintain anesthesia process under the monitoring of BIS. Propofol was used as the controls. Blood pressure and heart rate were recorded during operation. The VAS pain score was observed after surgery.To investigate whether this program can better maintain intraoperative hemodynamic stability, improve the quality of recovery, and reduce the incidence of postoperative adverse reactions.

Conditions

• General Anesthesia

Interventions

Type	Name	Description
DRUG	Etomidate	Etomidate will be used for general anesthesia
DRUG	Propofol	Propofol will be used for general anesthesia

Timeline

• Start date: 2021-05-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2022-02-04
• Last updated: 2024-06-05

Locations

1 site across 1 country: China