NCT05223738

Resident Memory T Cells in Vitiligo

Tissue Resident Memory T Cells in Early & Late Cases of Generalized Non-segmental Vitiligo

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 29 (actual)
• Sponsor: Kasr El Aini Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: —

Summary

This study aims to detect the presence and diversity of Tissue resident memory T cell populations in early and late cases of generalized non-segmental Vitiligo.

Detailed description

* Written informed consent obtained from every participant. * Detailed history taking including onset, course, duration of the disease, aggravating factors and received medications * VASI score assessed in every patient. * Patients photographed, divided into two groups early \& late cases and 3 mm punch biopsies will be taken from perilesional and non lesional skin. * Biopsies processed and stained for CD8 \& CD69 in cases of early group, \& late group and controls by immunofluorescence.

Conditions

• Vitiligo

Timeline

• Start date: 2020-12-31
• Primary completion: 2021-03-30
• Completion: 2022-02-01
• First posted: 2022-02-04
• Last updated: 2022-02-04

Locations

1 site across 1 country: Egypt