NCT05222854

Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma"

Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma" the CONGENIAL Analysis Sub-study of the GR

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Multicenter German- Registry of Incidental Gallbladder Carcinoma combining clinical real-world data and comprehensive genomic profiling. The registry collects medical data from clinical observation and molecular data derived from archival tumor tissue samples but does not define any medical intervention nor does it evaluate the efficacy or safety of the treatment decision made by the investigator.

Detailed description

In the largest cohort of IGBC patients ever analysed in such a comprehensive approach * determine the course of patients in this rare kind of cancer * combine cGP analysis of histological tumor samples with clinical real-life data to get a comprehensive overview on IGBC patients analysed and evaluate data to identify possible further (targeted) treatment possibilities * analyze potential risk factors associated with gallbladder carcinoma * assess the frequency of targetable mutations in IGBC

Conditions

• Gallbladder Carcinoma

Timeline

• Start date: 2017-10-11
• Primary completion: 2024-06-01
• Completion: 2099-12-01
• First posted: 2022-02-03
• Last updated: 2024-03-06

Locations

1 site across 1 country: Germany