NCT05222451

Nutrition for Asthmatics with Obesity

Nutritional Strategies to Enhance Lung Function in Asthmatics with Obesity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will test the effect of diet on asthma in individuals with obesity.

Detailed description

This is a crossover design pilot trial that will recruit 12 adults with obesity and asthma. Participants will undergo screening and a lead-in period before being randomized to a series of three, 7-day diets with a 7+ day washout period between each diet. Asthma control and lung function will be assessed at the completion of each diet. The goal of this pilot trial is to understand the effect of diet on asthma and conduct an exploratory analysis on factors that may predict the response to diet.

Conditions

• Asthma
• Obesity

Interventions

Type	Name	Description
OTHER	DGA Diet	A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans (DGA) Including: * A variety of vegetables and fruits * Grains, at least half of which are whole grains * Fat-free or low-fat dairy * A variety of protein foods, including seafood, lean meats and poultry, eggs, legumes, nuts, and seeds * This healthy eating pattern also limits saturated fats and trans fats, added sugars, and sodium.
OTHER	MCT Diet	A fully provisioned isocaloric, isonitrogenous study diet following the Dietary Guidelines for Americans supplemented with medium chain triglycerides (MCT).
OTHER	KETO Diet	A fully provisioned isocaloric, isonitrogenous ketogenic study diet.

Timeline

• Start date: 2022-06-27
• Primary completion: 2024-12-18
• Completion: 2024-12-31
• First posted: 2022-02-03
• Last updated: 2025-02-04

Locations

1 site across 1 country: United States