NCT05221684

Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer

Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer: a Retrospective Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This study aims to evaluate the value of the LNR as a prognostic indicator in patients with rectal cancer who offered total mesorectal excision.

Detailed description

Patients and methods Study design and setting This is a retrospective review of prospectively collected and maintained database of patients with CRC admitted in the Oncology Center of Mansoura University (OCMU), the Colorectal Surgery Unit of Mansoura University Hospitals, and the Department of General Surgery of Alexandria University. Selection criteria Patients of either gender aged 18 years or above who presented with rectal cancer of any stage will be included in the study. We will exclude patients with patients younger than 18 years; patients with synchronous colon cancer; synchronous liver, pulmonary or bones metastasis; or synchronous gastrointestinal cancer; or patients who were lost to follow-up. Study endpoints The primary endpoint of the study is to assess the value of lymph node ratio (LNR) on the oncological outcomes.

Conditions

• Recurrence

Interventions

Type	Name	Description
PROCEDURE	Lymph node harvesting	Lymph node harvesting after radical resection for rectal cancer with curative intent

Timeline

• Start date: 2020-06-09
• Primary completion: 2022-01-31
• Completion: 2022-12-31
• First posted: 2022-02-03
• Last updated: 2022-02-03

Locations

1 site across 1 country: Egypt