NCT05221567

Intensive Psychotherapy for Chronic Depression

The Effectiveness of Intensive Psychotherapy for Chronic Depression: A Naturalistic Comparison With Treatment-as-Usual

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 280 (actual)
• Sponsor: Modum Bad · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The study evaluates whether Intensive psychotherapy show superior effect on chronic depression over TAU

Detailed description

Background: Accumulating evidence indicates that intensive psychotherapy (i.e., greater number of treatment sessions per time unit) improves outcomes for patients with mental health problems. However, few studies have investigated whether patients with chronic depression (CD) benefit from treatment with higher intensity. The main purpose of this study is to investigate if intensive psychotherapy could improve treatment for patients with chronic depression (CD). The primary research question is whether two intensive psychodynamic inpatient treatments, affect phobia therapy (APT) and VITA, are superior to low intensity treatment (TAU) at completion of treatment. To indicate if a potential difference between intensive treatment and TAU is due to the intensity of the therapy, the study contrasts two therapies with similar intensity, but different theoretical rationales. Methods: 280 patients with CD are included in a naturalistic study. Patients are assessed at four time points; assessment, start of therapy, end of therapy and 1-year follow-up. Three comparisons are performed with patients matched across groups; Intensive treatment (APT + VITA) vs TAU during treatment, APT vs VITA during treatment and APT vs VITA during follow-up. The outcome measure is the BDI-II.

Conditions

• Chronic Depression
• Persistent Depressive Disorder
• Recurrent Major Depression

Interventions

Type	Name	Description
BEHAVIORAL	Psychotherapy	Intensive psychotherapy (i.e., greater number of treatment sessions per time unit)

Timeline

• Start date: 2012-01-01
• Primary completion: 2017-12-31
• Completion: 2017-12-31
• First posted: 2022-02-03
• Last updated: 2022-02-03