NCT05220995

The Effects of Miminal Stimulation Protocol on Preimplantation Genetic Screening

The Effects of Miminal Stimulation Protocol on Clinical Outcomes of Advanced Maternal Aged Women With Preimplantation Genetic Screening

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Gokalp Oner · Academic / Other
• Sex: Female
• Age: 38 Years – 45 Years
• Healthy volunteers: Accepted

Summary

PGS has been the most effective method for embryo selection in IVF cycles. Euploidy rates decrease significantly with advancing maternal age (AMA). The dosage of gonadotropins also may be increased to recruit an adequate number of follicles in AMA women, minimal Stimulation Protocol (MSP) with the new combination of human menopausal gonadotrophin (hMG) and clomiphene citrate (CC) for controlled ovarian hyperstimulation is defined for poor ovarian response women. The aim of this study is to show minimal stimulation protocol affect euploidy and pregnancy rates in preimplatation genetic screening (PGS) cycles with single embryo transfer.

Conditions

• Preimplantation Genetic Screening

Interventions

Type	Name	Description
GENETIC	protocol	ovarian stimulation protocols on euploid rates were compared.

Timeline

• Start date: 2021-05-15
• Primary completion: 2022-01-23
• Completion: 2022-01-25
• First posted: 2022-02-02
• Last updated: 2022-02-02

Locations

2 sites across 1 country: Turkey (Türkiye)