NCT05220969

Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 95 (actual)
• Sponsor: St Mary's University College · Academic / Other
• Sex: Male
• Age: 12 Years – 40 Years
• Healthy volunteers: Accepted

Summary

A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury. This score was then compared with the incidence of injury between those with high, medium and low risk scores for each injury. The influence of different rates of growth, stages of physical maturation and loading exposure were then also included in the risk model to see if any interaction effects could be observed between genetic risk score and susceptibility to injury in different categories of growth, maturation and loading exposure.

Conditions

• Fractures in Children
• Apophysitis
• Muscle Strain
• Ligament Injury
• Tendon Injuries
• Genetic Predisposition

Interventions

Type	Name	Description
GENETIC	Total Genotype Risk Score	A total genotype risk score has been generated based on the results of previously observed genetic association studies

Timeline

• Start date: 2019-12-01
• Primary completion: 2021-07-31
• Completion: 2021-07-31
• First posted: 2022-02-02
• Last updated: 2022-02-02

Locations

2 sites across 1 country: United Kingdom