NCT05219851

The Risk Factors for Acute Radiation Pneumonitis in Patients With Prior Receipt of Immune Checkpoint Inhibitors

The Risk Factors for Acute Radiation Pneumonitis in Patients With Prior Receipt of Immune Checkpoint Inhibitors.in Real-world Clinical Practice: a Multicenter, Prospective, Open, Non-interventional Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: Hubei Cancer Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of this non-interventional study is to collect data on the risk factors for acute radiation pneumonitis in patients with prior receipt of immune checkpoint inhibitors.

Detailed description

1. Incidence of acute radiation pneumonitis (aRPs) in in patients with prior receipt of immune checkpoint inhibitors. 2. Risk factors (especially analysis of the dosimetric risk factor) which may affect the product of aRPs events. 3. Establish a model to predict aRPs and guide clinical treatment.

Conditions

• Cancer Patients

Interventions

Type	Name	Description
RADIATION	Cancer patients underwent thoracic intensity-modulated radiotherapy	Cancer patients underwent thoracic intensity-modulated radiotherapy, previously received ICIs

Timeline

• Start date: 2022-06-01
• Primary completion: 2025-03-31
• Completion: 2025-10-31
• First posted: 2022-02-02
• Last updated: 2024-03-15

Locations

1 site across 1 country: China