Clinical Trials Directory

Trials / Completed

CompletedNCT05219253

A Study on the Immune Response and Safety of a Vaccine Against Herpes Zoster in Adults Aged 50 Years and Older in India

A Phase 3, Randomised, Observer-blind, Placebo-controlled, Multi-centre Study to Evaluate the Immune Response and Safety of the Herpes Zoster Subunit Vaccine When Administered Intramuscularly on a 2-dose Schedule in Adults Aged 50 Years and Older in India

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
288 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
50 Years
Healthy volunteers
Accepted

Summary

The purpose of this study was to evaluate the humoral immunogenicity and safety of 2 doses of GSK Biologicals' Herpes Zoster subunit vaccine (HZ/su) administered for the prevention of Herpes Zoster (HZ) in adults aged 50 years of age (YOA) or older from India.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHZ/suTwo doses of the HZ/su vaccine administered intramuscularly, one each at Day 1 and Month 2.
DRUGPlaceboTwo doses of Placebo (lyophilised sucrose reconstituted with saline \[NaCl\] solution) administered intramuscularly, one each at Day 1 and Month 2.

Timeline

Start date
2022-02-02
Primary completion
2022-10-11
Completion
2022-12-12
First posted
2022-02-02
Last updated
2025-05-15
Results posted
2024-04-08

Locations

9 sites across 1 country: India

Source: ClinicalTrials.gov record NCT05219253. Inclusion in this directory is not an endorsement.