NCT05218278

NFL Dynamics as a Predictor Factor in Patients With Out of Hospital Cardiac Arrest

Dynamics of Light Chain of NFL as a Predictor Factor of Neurological Outcome in Patients With Out of Hospital Cardiac Arrest

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: University Medical Centre Maribor · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To investigate the pharmacodynamics of light chain of NFL in patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Detailed description

To investigate the serum levels of the light chain of NFL at different time points after ICU admission (12, 24, 30, 36, 42, 48 hours after ICU admission) patients with out-of hospital cardiac arrest after successful resuscitation and determine the difference in the serum levels of NFL in patients with favorable neurological outcome compared to those with non-favorable neurological outcome.

Conditions

• Out-Of-Hospital Cardiac Arrest
• Neurological Injury

Timeline

• Start date: 2022-01-01
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2022-02-01
• Last updated: 2025-03-30

Locations

1 site across 1 country: Slovenia