NCT05213455

Booster Effect of mRNA Vaccine on Antibody Response for SARS-CoV-2 After Complete Vaccination With Sinos

Booster Effect of mRNA Vaccine After Complete Vaccination With Sinos: an Observational Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 150 (actual)
• Sponsor: Lahore General Hospital · Other Government
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

In most parts of the world, mRNA vaccines were used to provide protection to population against COVID 19. However, in some countries, including Pakistan, traditional viral vaccines named as Sinovac and Sinopharm were used for mass level immunization. Though these vaccines were approved by WHO, their efficacy had been questioned. Now after recommendation of booster doses, we aim to see the effect of mRNA vaccine as a booster dose after Sinovac and Sinopharm in terms of antibody response. (IgG RBD SARS CoV2)

Detailed description

In most parts of the world, mRNA vaccines were used to provide protection to population against COVID 19. However, in some countries, including Pakistan, traditional viral vaccines named as Sinovac and Sinopharm were used for mass level immunization. Though these vaccines were approved by WHO, their efficacy had been questioned. Now after recommendation of booster doses, we aim to see the effect of mRNA vaccine (BNT162b2, pfizer) as a booster dose after Sinovac and Sinopharm in terms of antibody response. (IgG RBD SARS CoV2). The antobody IgG RBD levels will be checked before the booster dose and then after 3 weeks of the booster.

Conditions

• Vaccine Reaction

Interventions

Type	Name	Description
BIOLOGICAL	booster vaccine for COVID 19	The effect of Booster vaccine will be seen in participants in terms of antibody response IgG

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-02-28
• Completion: 2022-03-15
• First posted: 2022-01-28
• Last updated: 2022-03-02

Locations

1 site across 1 country: Pakistan