NCT05212506

Correlation Analysis of Covid-19 IgG Antibody Level in Seminal Plasma and Semen Index

Association of Seminal Plasma SARS-Cov19 IgG Level With Semen Parameters and Embryological Characteristics in Vaccinated Normozoospermic Men

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Shanghai First Maternity and Infant Hospital · Academic / Other
• Sex: Male
• Age: 22 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Since December 2019, more and more cases of unexplained pneumonia appeared after exposure to the South China Seafood Market in Wuhan City, Hubei Province. Later, the disease were confirmed to be acute respiratory infectious diseases caused by the 2019 new coronavirus infection. Even though we have had great victories in the war against this pandemic, there is still a very large number of deaths early on. As research progresses, vaccines for this infectious disease are already being developed. There are currently two vaccines in widespread use worldwide: mRNA vaccines and inactivated vaccines. In China, inactivated vaccines are more commonly used. At present, some studies believe that mRNA vaccine does not affect the pregnancy rate and abortion rate of women, but the study sample size is small, and the conclusions are limited. The effects of inactivated vaccines on fertility are still in the blank. We now hope to conduct prospective studies, mainly to study the effect of inactivated vaccine injection on male semen, and whether it has an effect on the quality of embryos in IVF patients

Conditions

• Covid-19
• IgG Antibody
• Semen Index

Interventions

Type	Name	Description
BIOLOGICAL	vaccinated and unvaccinated	the vaccinated :Male patients who received more than 2 injections of the covid-19 vaccine;the unvaccinated :Male patients who did not receive the covid-19 vaccine

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-03-31
• Completion: 2022-05-01
• First posted: 2022-01-28
• Last updated: 2022-01-28

Locations

1 site across 1 country: China