NCT05212480

Evaluation of the Efficacy and Safety of Zinc in Viral Infections

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 460 (actual)
• Sponsor: University of Monastir · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

The main objective of the clinical study is to evaluate the efficacy of Zinc supplementation in non-critically ill Covid-19 patients..

Detailed description

The VIZIR study is a national, longitudinal, multi-centre study conducted over a 3-month follow-up period. The priori hypothesis was that supplementation with zinc would reduce 30-day mortality and need to intensive care unit (ICU) admission among non critically ill patients with Covid-19. The VIZIR study will be carried out in Tunisia at the level of consultations of general practitioners of both sectors : public and liberal, as well as in the emergency services of Monastir and Sousse.

Conditions

• SARS-CoV2 Infection

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Zinc	For each patient included, a prescription regimen of zinc (in bisglycinate form) is proposed at a dose of 25 mgtwice a day for 15 days for the intervention arm. This dose of zinc is to be taken away from meals.
DIETARY_SUPPLEMENT	Placebo	For each patient included, a prescription of an identical to the intervention arm concerning shape, smell, taste and color pill of placebo . This dose of zinc is to be taken away from meals.

Timeline

• Start date: 2022-02-15
• Primary completion: 2022-05-04
• Completion: 2022-05-04
• First posted: 2022-01-28
• Last updated: 2023-03-16

Locations

1 site across 1 country: Tunisia