NCT05210556

Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 778 (actual)
• Sponsor: WellSpan Health · Academic / Other
• Sex: Female
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.

Detailed description

This is a retrospective chart review study. Patients who underwent scheduled intra-abdominal surgery with a WellSpan gynecologic oncologist will be identified and their chart reviewed for demographic data of age, race, BMI, comorbidities, and type of surgery. Those patients who had a deep organ/space surgical site infection within 30 days postoperatively will be identified. The numbers of these infections before and after August 2020, at which time all patients moving forwards were prescribed antibiotic bowel preparation, will then be statistically analyzed and compared to see if the institution of the antibiotic bowel preparation was associated with a reduction in surgical site infection.

Conditions

• Surgical Site Infection
• Surgical Complication
• Gynecologic Cancer

Interventions

Type	Name	Description
OTHER	Diagnosed with Surgical Site Infection	As an observational study, this notates patients who were diagnosed with a deep organ/space surgical site infection within 30 days of surgery

Timeline

• Start date: 2021-12-22
• Primary completion: 2022-02-01
• Completion: 2024-06-30
• First posted: 2022-01-27
• Last updated: 2025-03-28

Locations

1 site across 1 country: United States