NCT05210465

Objective Confirmation of thе Anti-ischemic Effectiveness of Trimetazidine 80mg Once Daily in Patients With Stable Angina Who Had a History of Myocardial Infarction (METHOD)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 36 (actual)
• Sponsor: Servier Russia · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

METHOD is a prospective observational program that will be conducted in 1centre of the Russian Federation. Prospective follow-up will be for about 6 months. The METHOD study is a 2 visit study with first visit of inclusion and second visit of completion of the study. Patients with stable angina pectoris eligible to the study inclusion criteria will be invited to participate in this observational program. The parameters for analysis will be collected by doctors and entered into CRF. The final analysis will include data from patients who were taking TMZ 80 mg OD during the observational period. The decision to stop the study will be made once 36 patients receiving treatment with trimetazidine 80 mg OD will have been evaluated at V1. It is expected that 5 cardiologists will participate in the program. The planned number of patients is 36.

Detailed description

To describe antiischemic and antianginal effectiveness of trimetazidine OD 80 mg as well as adherence to the treatment with TMZ 80 mg OD in patients with stable angina pectoris and prior MI in real clinical practice in Russia

Conditions

• Coronary Artery Disease

Interventions

Type	Name	Description
OTHER	speckle tracking mode of the stress ECHO test with dobutamine	speckle tracking mode of the stress ECHO test with dobutamine

Timeline

• Start date: 2022-03-03
• Primary completion: 2023-11-01
• Completion: 2024-04-17
• First posted: 2022-01-27
• Last updated: 2024-04-18

Locations

2 sites across 1 country: Russia