NCT05209958

The Effect of Preoperative NLR Level on Epidural Analgesia Application in Thoracotomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Karadeniz Technical University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate the relationship of preoperative Neutrophil/Lymphocyte Ratio (NLR) with postoperative pain and the effect of preoperative NLR level on timing of epidural analgesia in thoracotomy.

Detailed description

The study was conducted prospectively in 60 patients aged 18-75 years, ASA I-III, who underwent thoracotomy. The patients were divided into 2 groups as NLR level above 2 (Group A) (n:32) and NLR level below 2 (Group B) (n:28). Each group was divided into subgroups with equal numbers of Prempative analgesia group and control group. Local anesthetic was administered to the preemptive analgesia group (Group P) 20 minutes before the surgical incision through the epidural catheter, and to the control group (Group K) 20 minutes before the patient was awakened from the epidural catheter. NRS levels and additional analgesia needs were recorded at 2, 4, 8, 12 and 24 hours postoperatively.

Conditions

• C23.550.767.700
• C23.550.470

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Neutrophil Lynphosite ratio	The patients were divided into 2 groups as NLR level above 2 (Group A) (n:32) and NLR level below 2 (Group B) (n:28).

Timeline

• Start date: 2020-06-10
• Primary completion: 2021-09-01
• Completion: 2022-01-10
• First posted: 2022-01-27
• Last updated: 2022-01-27

Locations

1 site across 1 country: Turkey (Türkiye)