NCT05209841

Heparinization vs Salinization of the Peripheral Venous Catheter

Heparinization vs Salinization of the Peripheral Venous Catheter: a Randomized Clinical Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,450 (estimated)
• Sponsor: Consorci Sanitari de l'Alt Penedès i Garraf · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Randomized, double-blind clinical trial to compare the efficacy of catheter sealing with saline, compared to low-dose heparin. 3,450 patients hospitalized at the Hospital Residencia Sant Camil, in Catalonia (Spain), will be randomized to each branch of study. The primary outcome will be the percentage of catheters removed due to obstruction in each branch of study. As secondary outcomes, the number of catheter-associated phlebitis, catheter-associated bacetrihemia, extravasation, and catheter loss will be measured. For the primary outcome, a superiority analysis will be carried out in terms of the percentage of obstructed catheters in each branch of the study.

Conditions

• Catheter Complications

Interventions

Type	Name	Description
DRUG	Low dose heparin	Catheters will be sealed with 3 mL of Fibrillin Ⓡ (heparin 20UI/mL)
DRUG	Normal saline	Catheters will be sealed with 3mL of 0.9% sodium chloride

Timeline

• Start date: 2022-04-05
• Primary completion: 2026-07-30
• Completion: 2026-07-30
• First posted: 2022-01-27
• Last updated: 2025-06-25

Locations

1 site across 1 country: Spain