Trials / Completed
CompletedNCT05209100
Microbiome-Mediated Gut Dysfunction in Non-Alcoholic Fatty Liver Disease
A Case-Control, Observational, Proof of Mechanism Study to Define Microbiome-Mediated Gut Dysfunction Across the Spectrum of Non-Alcoholic Fatty Liver Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 38 (actual)
- Sponsor
- AdventHealth Translational Research Institute · Academic / Other
- Sex
- All
- Age
- 35 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
This study is designed to generate the first human evidence to date on microbiota encroachment in non-alcoholic fatty liver disease. In parallel, the investigators will establish a biobank that will allow future studies to reveal how encroachment is connected to host metabolism and liver physiology, including the composition and function of the fecal microbiome.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Sigmoidoscopy | During the sigmoidoscopy, biopsy tissue will be obtained for research purposes. Biopsies will be performed based on typical standard of care procedures without an antecedent bowel prep. |
Timeline
- Start date
- 2022-02-11
- Primary completion
- 2023-03-22
- Completion
- 2023-03-22
- First posted
- 2022-01-26
- Last updated
- 2026-04-03
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05209100. Inclusion in this directory is not an endorsement.