NCT05207878

Interhemispheric Connectivity and Compensation

Interhemispheric Communication and Compensation in Peripheral Nerve Injury

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to determine which parts of the brain make it possible for some people to move skillfully with their left non-dominant hand.

Detailed description

This is a one-visit study, in which right-handed participants (individuals with unilateral peripheral nerve injury to the right upper limb, and healthy controls) will complete surveys and perform movement tasks. Movement tasks will be performed inside and outside a magnetic resonance imaging (MRI) scanner. Some participants will also receive transcranial magnetic stimulation (TMS) to briefly interfere with these putative brain networks.

Conditions

• Peripheral Nerve Injury Upper Limb
• Healthy

Interventions

Type	Name	Description
OTHER	STEGA-MRI	Precision drawing task (movement assessment)

Timeline

• Start date: 2021-12-09
• Primary completion: 2025-08-01
• Completion: 2025-08-01
• First posted: 2022-01-26
• Last updated: 2025-10-09

Locations

1 site across 1 country: United States