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Trials / Active Not Recruiting

Active Not RecruitingNCT05206513

Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
86 (actual)
Sponsor
Neurocrine Biosciences · Industry
Sex
All
Age
6 Years – 70 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to evaluate the efficacy of valbenazine versus placebo on improving chorea in pediatric and adult participants who have dyskinesia due to cerebral palsy (DCP) with choreiform movements.

Conditions

Interventions

TypeNameDescription
DRUGPlaceboCapsule, administered once daily orally or via gastrostomy/gastrojejunostomy tube
DRUGValbenazineCapsule, administered once daily orally or via gastrostomy/gastrojejunostomy tube

Timeline

Start date
2022-04-15
Primary completion
2025-12-01
Completion
2026-06-01
First posted
2022-01-25
Last updated
2025-08-01

Locations

38 sites across 10 countries: United States, Argentina, Belgium, Brazil, Israel, Italy, Mexico, Poland, Portugal, Spain

Regulatory

Source: ClinicalTrials.gov record NCT05206513. Inclusion in this directory is not an endorsement.