NCT05205187

Gut Microbiota and Metabonomics

Multi-center and Multi-omics Mechanism Research of Gut Microbiota and Metabonomics in Borrmann Type IV Gastric Cancer

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 450 (estimated)
• Sponsor: First Hospital of China Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

To evaluate the correlation between gut microbiota and metabolites in Borrmann type IV gastric cancer; To find the effects of microflora and metabolites on target organs; To detect the mechanism of key flora and metabolite by in vitro and in vivo experiments; To construct models of gut microbiota and metabonomics by machine learning.

Conditions

• Stomach Neoplasms
• Gut Microbiota
• Metabolomics

Interventions

Type	Name	Description
PROCEDURE	Healthy control specimen collection	Collecting blood and feces from healthy population.
PROCEDURE	Non-Borrmann IV patient specimen collection	Collecting blood, feces and gastric cancer tissues from Non-Borrmann IV patients.
PROCEDURE	Borrmann IV patient specimen collection	Collecting blood, feces and gastric cancer tissues from Borrmann IV patients.

Timeline

• Start date: 2022-02-28
• Primary completion: 2024-01-01
• Completion: 2025-12-31
• First posted: 2022-01-25
• Last updated: 2022-01-25

Locations

6 sites across 1 country: China