NCT05201560

Efficacy and Safety of Butorphanol Tartrate Injection for the Patients With Mechanical Ventilation

Efficacy and Safety of Butorphanol Tartrate Injection for the Patients With Mechanical Ventilation:a Randomized and Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare the incidence of hospital-acquired infections between butorphanol and fentanyl.

Detailed description

Butorphanol can improve inflammation and promote the recovery of pro-inflammatory/anti-inflammatory cytokine balance.However, there is still a lack of relevant clinical studies on butorphanol and fentanyl for the incidence of hospital-acquired infections in ICU mechanically ventilated patients.The objective of this study was to evaluate the analgesic efficacy,safety and the incidence of nosocomial infection of butorphanol in mechanical ventilation patients between butorphanol and fentanyl.

Conditions

• Analgesia
• Hospital-acquired Infections

Interventions

Type	Name	Description
DRUG	Butorphanol Tartrate Injection	Patients of this group will receive Butorphanol Tartrate Injection
DRUG	Fentanyl	Patients of this group will receive Fentanyl

Timeline

• Start date: 2022-01-01
• Primary completion: 2023-01-01
• Completion: 2023-01-01
• First posted: 2022-01-21
• Last updated: 2022-01-21