NCT05198661

Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,500 (estimated)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.

Conditions

• Paraneoplastic Neurological Syndromes or Autoimmune Encephalitis

Interventions

Type	Name	Description
BIOLOGICAL	Collection of biological sample with sera, CSF, buffy coat, PBMC, plasma.	Blood is collected only one time by blood sample to obtain serum, buffy coat, plasma and PBMC. 2 \*4ml of blood on dry tube 2 \*4ml of blood on EDTA tube If possibility of delivery in 48 hours at the Centre of Biological Resources, 7\*4ml of blood on heparin tube If cerebrospinal fluid has been drawn for diagnosis, remaining sample available will be stored in the collection

Timeline

• Start date: 2022-08-02
• Primary completion: 2032-08-02
• Completion: 2032-08-02
• First posted: 2022-01-20
• Last updated: 2024-02-29

Locations

62 sites across 1 country: France