NCT05195996

Beta Blocker Effects in Traumatic Brain Injury

Beta Blocker Effects on Patients With Traumatic Brain Injury

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Menoufia University · Academic / Other
• Sex: All
• Age: 16 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The study will be conducted on polytrauma patient who are admitted from emergency room or postoperative with head trauma to evaluate effects of beta blocker on patients with TBI.

Detailed description

The study will be conducted on polytrauma patient who are admitted from emergency room or postoperative with head trauma . Patients will be randomly assigned into two groups by sealed envelope technique into two equal groups. Parameters assessment: * Length of ICU stay * Length of total hospital stay * CT scan to exclude another intracranial hemorrhage or increase in hemorrhage * Functional status will be assessed using the GCS * Hemodynamic data ( bl.p / hr ) * Crystalloid volume that patient need in 24h * Mortality rate

Conditions

• Trauma, Brain

Interventions

Type	Name	Description
DRUG	Propranolol	intravenous propranolol for case patients
DRUG	Saline	intravenous saline for placebo

Timeline

• Start date: 2021-10-01
• Primary completion: 2022-03-31
• Completion: 2022-05-31
• First posted: 2022-01-19
• Last updated: 2023-03-17

Locations

1 site across 1 country: Egypt