NCT05194748

Diaphragmatic Thickness and Pulmonary Function in Parkinson's Disease

Correlation of Diaphragmatic Thickness With Pulmonary Function in Parkinson's Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 37 (actual)
• Sponsor: Abant Izzet Baysal University · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: —

Summary

Ultrasound can give important information about the morphology of the diaphragm and the amount of contraction. Our aim, with the prediction that a restrictive pathology will occur in the pulmonary function with the addition of camptocormia in Parkinson's patients; to compare respiratory functions in Parkinson's patients with and without camptocormia, to investigate the correlation between ultrasonographically measured diaphragmatic thickness and pulmonary function test values.

Detailed description

Respiratory complications are one of the most common causes of death in Parkinson's patients. In Parkinson's disease, abnormal flexion of the thoracolumbar spine of 45° or more, which is called camptocormia, increases during walking or standing and disappears completely in the supine position. The prevalence of camptocormia among Parkinson's patients is about 7%. Camptocormia in Parkinson's disease is associated with significant disease disability, higher daily dopaminergic drug dosage, and cognitive impairment. Parkinson's patients with camptocormia often complain of shortness of breath, attributed to reduced pulmonary capacity due to limited chest expansion. Diaphragmatic dyskinesia in Parkinson's patients may also lead to a restrictive deterioration in respiratory functions. Diaphragmatic thickness indicates diaphragmatic contraction and is correlated with PFT. Our aim; It is a comparison of respiratory functions in Parkinson's patients with and without camptocormia.

Conditions

• Parkinson's Disease and Parkinsonism

Interventions

Type	Name	Description
OTHER	No intervention, observational only	No intervention, observational only

Timeline

• Start date: 2021-12-24
• Primary completion: 2023-01-01
• Completion: 2023-02-15
• First posted: 2022-01-18
• Last updated: 2024-04-26

Locations

1 site across 1 country: Turkey (Türkiye)