NCT05192577

Testing Protocol for Cold-sensing Fibers

Nerve Excitability Testing Protocol for Cold-sensing Fibers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Aalborg University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This project aims to evaluate whether electrical stimulation can modulate the cold detection threshold and the cold pain threshold. The hypothesis is that different electrical stimulation will either decrease or increase the cold threshold depending on the shape of the electrical stimulus. If a combination of electrical stimuli and cold stimuli could be used, this could lead to a novel method for estimating the excitability properties of cold-sensing fibers. The sub-project takes place in 1 session (1.5 hours).

Conditions

• Pain

Interventions

Type	Name	Description
OTHER	Electrical stimulation	At the beginning of the session, an electrode will be attached to the participant's ankle. Electrical stimulation will be applied to estimate the electrical perception threshold. This threshold will be used as condition stimuli when different thermal thresholds are assessed.

Timeline

• Start date: 2021-11-24
• Primary completion: 2023-01-30
• Completion: 2023-07-03
• First posted: 2022-01-14
• Last updated: 2023-08-02

Locations

1 site across 1 country: Denmark