NCT05191745

Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery

Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery: A Randomized, Controlled, Double-Blinded Clinical Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Jewish General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized, double-blind, controlled clinical trial is to evaluate the duration of efficacy of parasternal blocks with the use of local anesthetic adjuncts for analgesia after coronary artery bypass grafting surgery.

Detailed description

This study will randomize patients to either standard pain control protocols or parasternal blocks after coronary artery bypass grafting-only surgery. This study will specifically examine the effectiveness and duration of analgesia of parasternal blocks with local anesthetic adjuncts, Dexamethasone 10mg and Dexmedetomidine 50mcg, added to the local anesthetic mixture

Conditions

• Coronary Artery Bypass Graft Surgery

Interventions

Type	Name	Description
DRUG	Parasternal blocks	Parasternal block with Bupivacaine 0.25% + Epinephrine 1:200,000 x 60cc + Dexamethasone 5mg and Dexmedetomidine 50mcg
DRUG	Standard of care	All standard management of postoperative pain, as per local protocols

Timeline

• Start date: 2022-01-26
• Primary completion: 2023-04-28
• Completion: 2024-06-01
• First posted: 2022-01-13
• Last updated: 2024-06-10

Locations

1 site across 1 country: Canada