Clinical Trials Directory

Trials / Completed

CompletedNCT05187273

Hemodynamic Optimization Based on a Dynamic Elastance Protocol

Intraoperative Fluid Optimization Based on a Dynamic Elastance Protocol During Major Abdominal Surgery: a Randomised Control Trial

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
46 (actual)
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery. Hence investigators created two groups: in the intervention group fluids are given in fluid-responders (SVV \> 13%) based on high value of dynamic elastance (ie. Eadyn \> 0.9). In the standard group fluids are administered when SVV \> 13%.

Conditions

Interventions

TypeNameDescription
BEHAVIORALElastance GroupFluids are given based on dynamic elastane value

Timeline

Start date
2021-02-25
Primary completion
2022-08-30
Completion
2023-12-30
First posted
2022-01-11
Last updated
2024-03-26

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT05187273. Inclusion in this directory is not an endorsement.