Trials / Completed
CompletedNCT05185167
Comparison of the Genotoxicity of Desflurane and Propofol
Genotoxic Effects of Desflurane and Propofol Anesthesia in Patients Undergoing Lumbar Disc Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Muğla Sıtkı Koçman University · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate if the anesthetics propofol and desflurane can damage DNA according to comet essay in patients submitted to lumbar disc surgery.
Detailed description
It is expected that DNA damage information provide the possible genotoxic effects of inhalational and intravenous anesthetics and contribute to the establishment of strategies aimed at reducing the risks to exposed patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Anesthetics, General Desflurane Maintenance | Comparison of dna damage of desflurane maintenance with propofol maintenance according to comet analysis |
| DRUG | Anesthetics, General Propofol Maintenance | Comparison of dna damage of propofol maintenance with desflurane maintenance according to comet analysis |
Timeline
- Start date
- 2022-01-17
- Primary completion
- 2022-03-15
- Completion
- 2022-03-20
- First posted
- 2022-01-11
- Last updated
- 2022-03-31
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT05185167. Inclusion in this directory is not an endorsement.