NCT05183763

Medication Adherence Program

Supporting Tailored Adaptive Change and Reinforcement for Medication Adherence Program: Randomized Trial of a Novel Approach to Improve Adherence in Older Hypertensive Women and Men

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 402 (estimated)
• Sponsor: Tulane University · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Randomized controlled trial testing the efficacy of the Supporting Tailored Adaptive change and Reinforcement for Medication Adherence Program (STAR-MAP), a health coaching approach that aims to improve antihypertensive medication adherence, blood pressure control, and quality of life. Participants (n=402) \>=40 years old with a diagnosis of hypertension, uncontrolled blood pressure, and low antihypertensive medication adherence will be recruited through a statewide health insurer, Blue Cross Blue Shield of Louisiana, and randomized to receive either interactive health coaching sessions with medication reminder tools (intervention) or medication reminder tools only (control) over one year. Data will be collected from participants at baseline, 6 months, 12 months, and 24 months using questionnaires, physical measurement (height, weight, blood pressure), a computer-based single-category implicit association test, and laboratory analysis of antihypertensive medication urinary metabolites.

Conditions

• Hypertension
• Medication Adherence
• Behavior and Behavior Mechanisms

Interventions

Type	Name	Description
BEHAVIORAL	STAR-MAP health coaching	Interactive health coaching delivered in 11 sessions over one year; focusing on using adaptive change tactics to improve medication-taking behavior
BEHAVIORAL	Medication reminder tools	Medication-taking reminder app and pillbox

Timeline

• Start date: 2022-03-07
• Primary completion: 2026-04-30
• Completion: 2027-04-30
• First posted: 2022-01-11
• Last updated: 2025-03-20

Locations

5 sites across 1 country: United States