NCT05183308

Combined Drug Therapy in Lateral Fragility Fractures of the Femur

The Effect of Combined Drug Therapy in Lateral Fragility Fractures of the Femur:a Clinical Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · Academic / Other
• Sex: All
• Age: 60 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

It was conducted a prospective study with a series of 50 patients treated by intramedullary nail using Clodronic acid and Vitamin D (study group including 25 patients) and patients with the same fractures treated with Vitamin D alone (control group including 25 patients). One independent observer performed clinical, biochemical and functional evaluations at T0 (1st day post-surgery) and at T1 (12 months later) Biochemical markers (serum calcium level, serum phosphate level, PTH (parathormone), Vitamin D, serum C-terminal telopeptide), VAS (Visual Analogic Scale) and HHS (Harris Hip Score) score, and femur densitometric views were administered at each evaluation.

Conditions

• Femur Fracture

Interventions

Type	Name	Description
DRUG	Clodronic Acid	Osteoporotic fracture treated with surgical and medical therapy

Timeline

• Start date: 2019-05-01
• Primary completion: 2020-03-01
• Completion: 2020-03-01
• First posted: 2022-01-10
• Last updated: 2022-02-04

Locations

1 site across 1 country: Italy