NCT05183061

Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt

Factors Associated With Post-induction Hypotension in Idiopathic Normal Pressure Hydrocephalus (iNPH) Patient Undergoing Ventriculoperitoneal (VP) and Lumbar Peritoneal (LP) Shunt

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 426 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand. The sample size calculation was based on the rule of thumbs of the logistic regression comprising 18 risk factors. The incidence of post-induction hypotension according to our institution's pilot study November 2019-January 2020) was 47%. With 10% addition for missing data and other possible reasons, the sample size was 426. The primary objective of the study is to report the factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures. Our secondary objective is to determine the incidence of post-induction hypotension in these patients.

Conditions

• The iNPH Patients Scheduled for VP or LP Shunt Procedures

Interventions

Type	Name	Description
DRUG	Ehedrine Norepineprine	No interventions required considering that this was a retrospective study.

Timeline

• Start date: 2021-06-01
• Primary completion: 2021-11-30
• Completion: 2021-12-20
• First posted: 2022-01-10
• Last updated: 2022-01-10

Locations

1 site across 1 country: Thailand